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The Value Express Scripts Delivers

A prescription drug doesn’t work if it’s priced out of reach. Express Scripts fights to ensure clients and consumers have access to safe, effective and affordable medications and life-sustaining or life-saving therapies.

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Pharmacy employees

Working on client terms and defending consumer wallets

Express Scripts offers clients multiple options to support the unique needs of their populations.

Clients have complete control and flexibility to choose their specific benefit design, network and pricing structure. Employers, health plans, labor unions, government organizations and many others partner with us because of the significant value we create by:

Negotiating rebates and discounts from drug manufacturers and providing formulary management services

Negotiating reimbursement rates and reduced fees with thousands of retail pharmacies nationwide to create industry-leading pharmacy networks

Encouraging the use of generics, biosimilars and more affordable brand-name drugs

Managing high-cost specialty medications with high-touch clinical care coordination

Improving population health, reducing waste and increasing clinically appropriate medication adherence

If we didn’t provide significant value for our thousands of partners, we wouldn’t exist.

Who we are

employees across 20 sites in the U.S.
patient service advocates
of pharmacists, doctors and nurses with specialties by disease state

Who we serve

1 in 3
commercial employers
health plans and government employers
Medicare Advantage plans
Medicaid plans in 13 states
PBMs and wholesale market participants

Industry-leading and first-to-market innovations that matter

Patient Assurance® program

First in the industry to cap the out of pocket cost of insulin at $25 for a 30-day supply

Copay AssuranceTM plan

Caps out of pocket cost at $5 for generics and specialty generics, $25 for preferred brand drugs, $45 for preferred specialty brands under a client’s prescription drug benefit


Fully transparent client pricing model with 100% rebate and spread pass through—proven to drive lower drug trend and total medical costs

Embarc Benefit Protection®

Makes multi-million dollar gene therapies more affordable with $0.99 PMPM flat fee and $0 out-of-pocket cost

Health Connect360®

Performance-based clinical solution driving $399 PMPY1 and gaps-in-care closures 14x faster


Value-based program that saved clients $6.4B3 in 2022 through lower medical and drug costs


Expands rural health access via independent pharmacies—offering greater reimbursements and care services, while enhancing support with industry-first Independent Pharmacy Advisory Committee

Express Scripts ClearNetwork

Standardizes and simplifies payments to pharmacies with industry benchmark pricing for prescription drugs

Driving better clinical outcomes for those we serve

Preventing thousands of incidents of stroke, heart failure and other serious health issues per year through our clinical programs

Driving >80% adherence rates4 across the majority of specialty Therapeutic Resource Centers

Developing >2.4M safety interventions5, preventing adverse events and hospitalizations for patients each year

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Express Scripts, a key part of The Cigna Group, provides critical value-added health services to meet the evolving needs of stakeholders across the U.S.
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  1. Evernorth Health Connect360, “Making connections that count

  2. Evernorth Health Connect360

  3. SafeGuardRx | Home (Evernorth Data)

  4. Accredo Specialty data, Book of Business Average 2021

  5. RationalMed data, 2020 Express Scripts Book of Business