2026 annual formulary updates
Express Scripts® Pharmacy Benefit Services continues its commitment to clinically appropriate, cost-effective prescription drug coverage. Annual changes to our formularies are available now.

2026 annual formulary updates
Our mutual clients are committed to having the most up-to-date, clinically appropriate and cost effective prescription drug coverage for their members. Because of our partnership with thousands of clients, we use our unmatched scale and proven track record to advocate on their behalf, leveraging negotiations to provide competitive pricing. When clinical considerations align with these opportunities, patients and payers benefit.

What you need to know
On January 1, 2026, we will exclude 50 additional products from the National Preferred Formulary, demonstrating our commitment to minimizing health care waste by excluding high-cost medications that may not provide greater clinical results.
On January 1, 2026, we will exclude 47 additional products from the Flex Formulary. The National Preferred Flex Formulary gives clients a pathway to cover alternative products with lower list prices.
1 Express Scripts claims data, 3/15/25-7/22/25
Annual changes to the Basic and High Performance Formularies
Additional opportunities were identified for Basic and High Performance to help client and member savings. Detailed 2026 annual status updates for these formularies are now available.
Supporting clients and their members
The small percentage of members being asked to switch to preferred medications will receive personalized outreaches, including a list of alternative medications and information on switching to a preferred product.

FOR CONSULTANT/BROKER USE ONLY. Please keep this information confidential and do not share outside of your firm.